Loew made the announcement with Germany to host Serbia on March 20 in a friendly, before playing a Euro 2020 qualifier away to the Netherlands four days later.
"The national team's young players will receive the space necessary to develop fully".
"It was important to me personally to explain to the players and managers of Bayern my thoughts and plans today", Low was quoted as saying to renowned Germany newspaper Bild.
"They are all still world-class players who are at the forefront of their club and guarantee success".
"We want to give the team a new look", Loew said. "Now it's up to them to take responsibility". "FC Bayern has great respect for the contributions of Thomas, Mats and Jerome to the national team and German football".
'We have had a long and - most of the time - successful career with the DFB and I think it's not a classy way if prefabricated statements from the DFB are published shortly after we learn about the coach's decision.
Loew's decision heralds the end of an impressive worldwide career for Mueller, who broke through as a raw 20-year-old at the 2010 World Cup and went on to score 38 goals in 100 appearances.
Bayern chief Karl-Heinz Rummenigge said he was "irritated" by the timing of Low's announcement.
Muller, 29, amassed 100 national team appearances, scoring 38 goals and registering 36 assists since making his debut in 2010 - while Boateng and Hummels picked up 76 and 70 caps respectively.
"I don't understand it at all", he said.
Germany's Thomas Mueller during the World Cup 2018. I was always proud to wear the jersey, I've given everything, I want to thank you for your support, it was an incredible journey'.
Writing on Twitter, Boateng said: "I'm sad to hear this news, as it was always the best thing of all for me to represent my country". Even so, I would have liked a different farewell for us, of course.
At the weekend, Low also indicated that goalkeeper Manuel Neuer, another Bayern star, could lose his place in the Germany squad.
"I was young myself and reliant on older players to make room for me".