The House is getting its first two Muslim women and MA is getting its first black congresswoman while Arizona and Tennessee stand to elect their first woman senators in Tuesday's midterm elections.
"I ran because of injustices and because of my boys, who are questioning their (Muslim) identity and whether they belong", Tlaib said in an USA television interview in August. She will succeed the first Muslim congressman, Keith Ellison, who vacated the seat to run for Minnesota's Attorney General.
A Somali-American and a former refugee, she served as the first Somali-American legislator in the US when she won a seat in the Minnesota House of Representatives in 2016.
And regardless of who wins in Arizona's competitive Senate race, the state will elect either Republican Martha McSally or Democrat Kyrsten Sinema as the state's first woman to serve in the chamber.
Omar's family fled Somalia in 1991 due to civil war.
She has stated that President Donald Trump's "politics of fear" motivated her to run for the seat.
Tlaib, the daughter of Palestinian immigrants, said in recent interviews that she favors a one-state solution to the Israeli-Palestinian conflict, as opposed to a two-state solution that would establish a Palestinian state alongside Israel.
The Democrat lived at the Daad refugee camp in Kenya for four years and could not even speak English at the time she relocated to the US.
Omar will not only be among the first Muslim women elected to Congress.
Tlaib's win comes after the 2016 election of Trump spurred a record number of women to put their names on the ballot.
While Omar campaigned on a similarly progressive platform, which calls for universal healthcare and tuition-free colleges.
She also has been mindful of the historic nature of her candidacy. "I can not wait to serve with you, inshallah", Omar, who also won her election, said on Twitter.