There was good news for Roma and Real Madrid before their Tuesday evening match had even kicked off, with both teams qualifying for the next round of the Champions League thanks to Viktoria Plzen's 2-1 win over CSKA Moscow.
As a result of a terrible start which saw Real Madrid's campaign get underway with a defeat in the UEFA Super Cup to crosstown rivals Atletico Madrid, Julen Lopetegui was sacked by the Whites and Santiago Solari was installed as his successor.
Gareth Bale celebrates after scoring Real Madrid's opening goal at the Stadio Olimpico.
And that terrible miss was punished 61 seconds into the second half by Bale.
What does it mean? However, on his first outing as the first team boss, Santiago Solari's Real Madrid side suffered a 3-0 defeat. Solari's men also lost at the weekend, going down 3-0 at Eibar in his first game as permanent head coach, but this was much more like their fluid best.
One clearance in the first half was miraculous and though Roma's rapid attackers caused Madrid problems in defence, the World Cup victor was solid.
The score-line didn't flatter the Basque side, and Madrid didn't even rest players ahead of this Champions League clash, either, with their starting line-up including the likes of Toni Kroos, Luka Modric, Gareth Bale, Marcelo and Sergio Ramos. How the 21-year-old managed to miss from around five yards out will remain a mystery.