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"Tehran will attack ten times more if attacked by enemies", who "don't want an independent Iran in the region", Khamenei said.

At a press conference following their talk, Ms Merkel said: "Our meeting focused on an worldwide issue, the Iran agreement". This is, of course, due to the fact that Iran and Russia's interests in Syria are not completely aligned, noticed mostly by reports that have been denied to varying degrees that Russian Federation and Israel have sought a deal regarding the withdrawal of Iranian forces from southern Syria.

"From some European countries we get the message that they expect the Iranian people to both tolerate the sanctions, deal with the sanctions, and go along with them and give up our nuclear energy activities and continue with the restrictions", he told an audience in a Tehran suburb. "We have to break their money machine", he said.

Media captionWhat is the Iran nuclear deal?

Iran's supreme leader Ayatollah Ali Khamenei on Monday warned European leaders against their "dream" of Tehran continuing to curb its nuclear programme while finding itself under new economic sanctions.

Israel continuously asserts that it will not allow Iran to entrench itself in Syria, where it has for years provided military backing to President Bashar al-Assad alongside Russian Federation.

In his statement at the press conference, Netanyahu stressed that permitting Iran to operate freely in Syria not only threatens the Jewish state, but also creates conditions that could increase the number of refugees fleeing to Germany. He added, "Iran and Syria have deep relations that can not be influenced by the propaganda actions of anyone". "All parts of Syria".

Netanyahu suggested the deal was bound to collapse without USA involvement, but said he agreed with Merkel that "Iran's aggressions" needed to be kept in check. She expressed unease over Iran's behavior referring to its regional activity and missile program.

Foes Iran and Israel have been kept at bay for decades.

With partners in Berlin, Paris and London still reeling from President Donald Trump's decision last month to exit the hard-fought 2015 accord, Netanyahu expected to seek European cooperation on a still-to-be-determined Plan B.

The Iran deal paved the way for the partial lifting of global sanctions against the country, in exchange for Tehran curbing its nuclear programme for a number of years.

Merkel said they were in agreement with Netanyahu on the need to prevent a nuclear-armed Iran, but had different views on the best way to achieve this.

Turning to the long-stalled Israeli-Palestinian peace process overshadowed by the recent string of clashes along the Gaza border where over 100 Palestinians were killed and slew of rockets were fired into Israel, Netanyahu said "our hand is always extended in peace".