"It wasn't an easy match", Williams said.
World number one Nadal had been two sets up but 0-3 down in the third to Bolelli when rain caused the tie to be suspended late Monday.
And, yes, the victory.
"Yeah, it feels like this suit represents all the women that have been through a lot mentally, physically with their body to come back and have confidence and to believe in themselves", she said.
In an Instagram following the match, Williams dedicated her first time back on the court to all the moms out there.
Because she missed so much time, Williams is ranked 451st after being No 1 for much of the previous years, including when she took leave in February 2017.
Playing her first Major since the birth of daughter Alexis Olympia on September 1, she is determined to show that the competitive fire still burns bright.
It sure seems like Serena Williams can do it all.
While dresses or skirts are generally the go-to look for female tennis players, some users have noted that Williams is not the first to break the norm - American Anne White donned a white bodysuit at Wimbledon in 1985; Williams herself at least practiced in one in 2011.
Both stars warmed up for the showdown with first-round doubles matches on Wednesday.
Pliskova got another opening early in the second set breaking Serena's serve for the first time in the match after a very long service game.
The 23-time major victor, who had not played on clay since 2016 after taking time away to have a baby, likened her outfit to something from Marvel's Black Panther and said the new look made her "feel like a super hero".
Williams stretches for a backhand.
Pliskova, a lefty whose twin sister upset Williams in the 2016 US Open semifinals, actually hit more aces, 15. In the victory, Serena won 81 percent of her first serve points and 39 percent of her second serve points.
"It's been two years since I played here".
Williams then trailed 0/3 before eventually taking the set when Pliskova, who had never won a match at the tournament in three previous visits, put a forehand wide. In 2016, Nadal withdrew with an injured left wrist after a pair of easy victories, then claimed every set he played past year en route to the trophy.
"It felt really good", said Australia's 17th seed. While some had doubts about whether the new mom would return to the game at all, the Grand Slam queen proved her doubters wrong and made her comeback yesterday in the most epic way imaginable.
Duckworth, who missed the French Open past year because of foot surgery, has never won a match at the clay-court event in four appearances.